Introduction to PROMIS [Presenter Name] [Event] [Date] What
Introduction to PROMIS [Presenter Name] [Event] [Date] What is PROMIS? Patient-Reported Outcomes Measurement Information System Measures used to evaluate and monitor physical, mental, and social health (adult & pediatric) Relevant across all conditions Developed and evaluated using state-of-the science
psychometric methods Now supported by HealthMeasures, the official information & distribution center for 4 NIH-supported measurement systems (PROMIS, Neuro-QoL, NIH Toolbox, & ASCQ-MeSM) Scores on one metric Translations available in Spanish & other languages HealthMeasures.net/PROMIS Essential Components of PROMIS DOMAIN ITEM BANK The feeling, function, or perception you
wish to measure Collection of items that each measure the same domain Cuts across different diseases and settings. E.g., physical function, depressive symptoms Used to create different measure types, all producing a score on the same
metric HealthMeasures.net/PROMIS PROMIS Measure Types SHORT FORMS COMPUTER ADAPTIVE TESTS (CATs) Subsets of item banks Focused on a single domain Off-the-shelf
or custom Usually 4-10 items Individually tailored electronic questionnaires Focused on a single domain Next item administered from item bank depends on previous answers Usually 4-12 items HealthMeasures.net/PROMIS
PROFILES Collection of short forms covering multiple domains (e.g. depression, physical function, pain interference) Adult profiles (29, 43, and 57 item versions), Pediatric and Parent-Proxy profiles (25, 37, 49 item versions)
Domains for Adult Assessment HealthMeasures.net/PROMIS Domains for Pediatric Assessment HealthMeasures.net/PROMIS Based on Item Response Theory (IRT) Assumes an individuals responses to items are related to an unobservable domain or trait (e.g. fatigue). IRT can use item responses to estimate a persons score on that domain, or expected responses to different items can be estimated from a persons score.
How fatigued were you on average? Not at all Energetic Very much Severe FATIGUE HealthMeasures.net/PROMIS Select, Obtain & Administer PROMIS
Measures HealthMeasures.net/PROMIS PROMIS is at HealthMeasures.net Official information & distribution center for PROMIS, Neuro-QoL, NIH Toolbox, & ASCQ-Me Search & View Measures: Download free, respondentready PDFs of PROMIS measures. Hundreds of measures available, all searchable by domain, preferred measure type, language, and more. Applications of HealthMeasures:
Free guides to help you select PROMIS measures for specific uses or patient populations (e.g., cancer) HealthMeasures.net/PROMIS Administration & Data Collection Using Paper Respondent-ready PDFs for short forms & profiles on HealthMeasures.net Minimal technology needed; staff time required for data entry and scoring Using a Computer Required for administration of CATs PROMIS measures available in REDCap, Epic, AOPOC (orthopedics), Assessment CenterSM
and OBERD (Outcomes Based Electronic Research Database) For a custom solution, the Assessment Center API allows your data collection system to administer PROMIS measures (including CATs) Using the PROMIS iPad App Enables on-demand assessments. An administrator can select any PROMIS measure and hand the iPad over to a respondent for completion Available in the iTunes Store HealthMeasures.net/PROMIS Score and Interpret PROMIS Measures
HealthMeasures.net/PROMIS PROMIS SCORING OPTIONS HealthMeasures Scoring Service Free, web-based application Upload Excel file w/ raw responses to short form or profile items Automatic Scoring via Data Collection Tool
Many data collection tools such as REDCap, Epic, and Assessment Center automatically score responses & deliver results Receive scored file by email Most accurate and preferred method for calculating scores
HealthMeasures.net/PROMIS By Hand Scoring Manuals provide details and instructions for scoring individual PROMIS measures Accessed using the Search & View Measures feature and Calculate Scores page on HealthMeasures.net
Understanding PROMIS Scores PROMIS measures use a T-score metric 50 is the mean for a relevant reference population 10 is the standard deviation (SD) of that population Meaning of the score is defined by how it compares to the scores of others in a reference population High scores equal more of the domain being measured (e.g., more fatigue, more physical function) HealthMeasures.net/PROMIS PROMIS Score Ranges HealthMeasures.net/PROMIS
Linking Measures Converts score from one measure to PROMIS metric Enables comparisons when different measures used www.prosettastone.org HealthMeasures.net/PROMIS PROMIS at Work HealthMeasures.net/PROMIS Examples of PROMIS at Work in Clinical Practice
Partners HealthCare: PROMIS measures in 24 adult and pediatric specialties Goal to expand use across Partners system by end of 2018 University of Rochester: Administered PROMIS CATs to nearly every orthopaedics patient since 2015. Results viewed immediately in Epic Over 1,000,000 evaluations collected (as of April 2017) New South Wales, Australia: Integrated Care Strategy administers the PROMIS Global Health scale to patients for direct, timely feedback about their health HealthMeasures.net/PROMIS Examples of PROMIS at Work in Clinical Research Between 2012 and 2017, PCORI has awarded $27 million to studies using
PROMIS measures The NIH-funded Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium is conducting multiple validation studies Populations include children with asthma, atopic dermatitis, rheumatic disease, cancer, inflammatory bowel disease, sickle cell disease, and diabetes. Two-part series in the journal Psychological Test & Assessment Modeling (2016) provided strong evidence supporting measurement equivalence of PROMIS short forms in diverse groups of cancer patients HealthMeasures.net/PROMIS Examples of PROMIS at Work in Evaluating Quality of Care
The American Academy of Orthopaedic Surgeons recommends PROMIS among its Instruments for Collection of Orthopaedic Quality Data The Mayo Clinic recommends and uses the PROMIS Global Health scale as a patient-reported outcome for Quality of Care Assessment for patients receiving care at Mayo The FDAs Clinical Outcome Assessment (COA) Compendium, a resource to foster patient-focused drug development, includes PROMIS Physical Function in sarcopenia and oncology HealthMeasures.net/PROMIS Join the HealthMeasures Listserv Visit HealthMeasures.net or email [email protected] to join! Receive emails w/ newsletter, upcoming
conferences and educational events about PROMIS HealthMeasures.net Acknowledgments Funding for HealthMeasures was provided by the National Institutes of Health grant U2C CA186878. PROMIS, Patient-Reported Outcomes Measurement Information System, NIH Toolbox, NIH Toolbox for the Assessment of Neurological and Behavioral Function, ASCQ-Me, Adult Sickle Cell Quality of Life Measurement Information System, and their marks are owned by the U. S. Department of Health and Human Services.
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