Αξιοπιστία Εργαστηριακού Αποτελέσματος.

Αξιοπιστία Εργαστηριακού Αποτελέσματος.

. & - K., : - -

- , , , (..) : :

( , , ) ( , ., , ). : ( , , , ).

, (reliability) . , .

. : - (accuracy) - (Precision)) - (reproducibility) - (Practicability) - )

. : - (Sen)sitivity) - (Specificity) - (Accuracy) . : (d) () (x) (d = x) (d = x) (d = x),

R = (d / ) 100). Stan)dard Solution)s ( con)trol solution)s ) . , . , . . Accuracy .

(precision)) : . ().

. precision) accuracy . truen)ess , accuracy.

( ) 2002/657/ ( ), precision) . , fidelity precision). ""

( ) . , fidelity precision) . ;

() () precision ( accuracy=) =repeatability.

. . accuracy . Precision) vs Accuracy

E A . E (con)sisten)cy). .

- Precision , , , , Accuracy . Reproducibility (reproducibility)reproducibility) ,

, , , , . - - , . , , H

_ 1. (. ). S Stan)dard Deviation), . (reproducibility) )

H CV (Coefficien)t of Variation)) S CV= ------- x) (d = x 100 _ x) (d = x

() (Stan)dard Deviation)). . , . . .

(reproducibility)+/-) 95,5% . (precision) : SD ( S= ). o (coefficien)t of variation), CV), (S / x) (d = x ).

(coefficien)t of variation), CV), : CV % = (S / x) (d = x ) 100. , , . : CV SD _

mg/dl _ - _ 2 ( -) 1 37

1 1 2 33 -3 9 3 40 -4 16 .

7 36 0 0 8 35 1 1 _ _

291:8=36= (-)2 =63 Stan)dard Deviation) ( ) S= . 63:7=3 95,5% 36 +/- 6 36-42, . CV=(3:36)100= 8,3% ( *)

* %CV 1s,2s,3s 1s,2s,3s (Practicability) : . .

. . . . (L,M,H con)trols) ( stan)dard calibrator solution)s).

.

E (sen)sitivity) (N) (sen)sitivity) , , .

. A ,

(detection limit). E () ()

% ={ /(+)} 100 (SPECIFICITY)) - . Hb,Bil, turbidity, medicin)es, immunoglobulins , cross

reaction)s. . . % () () () . = (/+) 100 100% 100% .

(predictive value) + + . PV(+)={ /+} 100

100, . . (predictive value) .

PV(-)= {AA/+} 100 , 100 . . (Diagn)ostic Value) :

: (Diagn)ostic Value)

: () .(vidal-) ( - - . . :H . (. ), ,

(PV+ . ). . .

, , (Levey-Jen)n)in)gs,Y)ouden)) . (Quality Assuran)ce of Testin)g Results) : - , / (day to

day) (batch to batch). -K (reproducibility)Internal QC).). - (reproducibility)Proficiency Testing) - (reproducibility)External QC).). .

(REPLICATES , . () .

() . : 1 2 (r = 2,8 s), . 15-20 ( ) _

x) (d = x s. , _ x) (d = x (1, 2, ...) .

. 2s ( ) 3s ( ). (con)trol) .

( ). . :

1 (3s) , . 2 ()

. 10 , . .

. Levey-Jen)n)in)gs LeveyJen)n)in)gs . 3

(.. ) (.. ). Levey-Jen)n)in)gs Westgard

Westgard Levey-Jen)n)in)gs. . : 12s :- 2 3

13s : - 3 22s : 2 3

R4s : 4 41s : 1 _ 10 X :

O O (Stan)dard Deviation) In)dex) (d = x SDI) . SDI . SDI -2 2. :

SDI SDI : . .

. . . SDI . .

SDI LeveyJen)n)in)gs. SDI . SDI . . SDI SDI

. SDI .

. Y)oden) plot , . , , . 2 s 4s. / ,

2 s . . Y)oden)

, . ,

. T , Laboratory information systems (LIS ) . , , , , , (QC).), .. barcodes

. : http://www.esyd.gr/pweb/s/20/files/kan)on)ismoi/kr itiriaOdigies/KO_KLINERG.pdf

EN ISO 15189:2012 : http://www.esyd.gr/portal/p/esyd/el/article_previe w.jsp?arcluid=2985 ... To ... ISO,

. .

, , , . . -- . . . . . (, ) ,back up , . , , .

Deadlin)e 01.01.2014 EN ISO 15189:2012. 3. (, , ), 31.12.2014, ( EN ISO 15189:2007 EN ISO 15189:2012). 4. 01.01.2015 EN ISO

15189:2012. 25 , ISO, ,

, . My slideshare.n)et page http://www.slideshare.n)et/x) (d = xartopon)tikas

Recently Viewed Presentations

  • Teaching Philosophy - Nanyang Technological University

    Teaching Philosophy - Nanyang Technological University

    X = gx Y = gy KA = Yx = gxy KB = Xy = gxy MAN-IN-THE-MIDDLE ATTACK The adversary is able to derive both KA and KB X = gx Y' = gy' KA = Y'x = gxy' KB...
  • ABOR Learner-Centered Education Course Redesign Initiative Workshop IV

    ABOR Learner-Centered Education Course Redesign Initiative Workshop IV

    Nice seating and visual aids. It's cool to work across the table and interact with everyone and learn from each other. Interview- Student New Classroom In the traditional classroom, students did not sit in teams, which made it difficult for...
  • Discover Universal Design for Learning (UDL) to respond

    Discover Universal Design for Learning (UDL) to respond

    Responding to learner diversity: removing barriers to learning. Inclusion is an ongoing process that aims to increase access and engagement in learning for all students by identifying and removing barriers. (IBO, 2010)
  • GHSGT Common Prefixes and Suffixes

    GHSGT Common Prefixes and Suffixes

    Medical Terminology: Root Words, Prefixes, and Suffixes Smyrna Health Science
  • CFM S4 Configuration - CFM-Core Integration

    CFM S4 Configuration - CFM-Core Integration

    Accessing NORM Configuration. Select Administration, then NORM Configuration. Using NORM Configuration. Use the drop-down menus for Region, Branch, or Device Model to narrow your search. Selecting Search without additional criteria will return all NORM devices.
  • Mr Blacks Animated Maths Notes Using Mr Bartons

    Mr Blacks Animated Maths Notes Using Mr Bartons

    Using Mr Barton's original notes. 8. Constructions ... Constructions are what maths used to be all about before computers came in and made life just . a bit too easy! The Ancient Greeks and the Egyptians were fascinated by constructions,...
  • Audit Overview - Solanco School District

    Audit Overview - Solanco School District

    Audit Overview. Audit in Accordance with: US Generally Accepted Auditing Standards. Government (Yellow Book) Auditing Standards. Uniform Guidance. Audit of period 7/1/15 - 6/30/16. Overview of Audit Process. Audit Findings: No significant deficiencies or material weaknesses are reported
  • Mean from a Frequency Table Calculating the Mean:

    Mean from a Frequency Table Calculating the Mean:

    During 3 hours at Heathrow airport 55 aircraft arrived late. The number of minutes they were late is shown in the grouped frequency table below. Grouped Data The Modal Class 2 50 - 59 4 40 - 49 5 30...